About IDRM

 The Institute of Developmental and Regenerative Medicine (IDRM) is a unique flagship institution, at the University of Oxford, dedicated to meeting an ambitious challenge: two thirds of all deaths world-wide are due to non-communicable diseases, many of which are cardiovascular, neurological or immune system disorders that have a developmental origin, representing an urgent unmet clinical need.  The mission of the IDRM is the development of new drugs and therapeutic strategies to tackle these chronic illnesses.

At its core is a formal merger of developmental biology and regenerative medicine in the form of 15-20 world leading research groups comprising 240 cardiovascular, neuroscience and immunology scientists integrating their expertise to foster multidisciplinary collaborations.  

The IDRM has four key goals:

• To further our understanding of the cellular and molecular processes that control normal development of the heart, brain and immune system
• To determine what causes congenital disease and increased susceptibility for disease acquired in adulthood 
• To identify therapeutic targets to reactivate resident cells for repair of the injured adult heart, brain and immune system 
• To establish new treatment strategies designed to replace and restore damaged tissues arising from birth defects or acquired adult disease.

To achieve these goals the IDRM will combine experimental and computational biology with machine learning, artificial intelligence platforms and mathematical modelling; working across disciplines with University colleagues in Big Data, Target Discovery, Maths and Biomedical Engineering and with clinicians at the John Radcliffe and Churchill Hospitals in Oxford. The IDRM is housed in the IMS-Tetsuya Nakamura Building in the Old Road campus site.

The IDRM comprises of world-class researchers from the Department of Physiology, Anatomy and Genetics (DPAG) and the Department of Paediatrics. DPAG cardiology researchers across eight core groups are situated on the British Heart Foundation Cardiovascular Research floor. Paediatrics researchers make up three neurology, and one immunology, groups, spread over two floors of the Institute.